Reproductive Factors, Exogenous Hormones, and Pancreatic Cancer Risk in the CTS
نویسندگان
چکیده
منابع مشابه
Reproductive factors, exogenous hormones, and pancreatic cancer risk in the CTS.
Female steroid hormones are hypothesized to play a protective role in pancreatic cancer risk. However, results from epidemiologic studies that examined hormone-related exposures have been inconsistent. The California Teachers Study is a cohort study of female public school professionals that was established in 1995-1996. Of the 118,164 eligible study participants, 323 women were diagnosed with ...
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چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولRisk Factors in Pancreatic Cancer
Pancreatic cancer is one of the most lethal malignant diseases with the worst prognosis. It is ranked as the fourth leading cause of cancer-related deaths in the United States. An unknown but important proportion of cancers develop in people who carry mutation in a cancer-predisposing gene. Identification of cancer-predisposing genetic mutations in susceptible individuals affords the opportunit...
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Sex is a consistent predictor of bladder cancer: men experience 2-4-fold higher age-adjusted rates than women in the U.S. and Europe. The objective of this study was to examine whether hormone-related factors are associated with bladder cancer in women. We examined parity, age at menarche, age at first birth, age at menopause, oral contraceptive use and menopausal hormone therapy (HT) use and b...
متن کاملParity, reproductive factors, and the risk of pancreatic cancer in women.
Incidence rates for pancreatic cancer are consistently lower in women than in men. Previous studies suggest that reproductive factors, particularly parity, may reduce pancreatic cancer risk in women. We examined parity, breast feeding history, age at first birth, menstrual factors, and exogenous hormone use in relation to pancreatic cancer risk in a prospective cohort study of women. Informatio...
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ژورنال
عنوان ژورنال: American Journal of Epidemiology
سال: 2013
ISSN: 0002-9262,1476-6256
DOI: 10.1093/aje/kwt154